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08/10/2025 | Scientific promotion

Scalable Approach to Evaluate Plant microRNA Trimming and Tailing from Small RNA-Seq Data
MicroRNAs are small regulatory RNAs of 20-24 nt, which guide the RNA-induced silencing complex to silence several genes post-transcriptionally. Plant miRNA biogenesis involves many steps, including their 2'-O-methylation at their 3' end, which protects them from degradation. In addition, there are two other types of modifications involved...

31/07/2025 | Scientific promotion

TCP10 acts downstream of light and retrograde signaling pathways to promote Arabidopsis cotyledon de-etiolation in concert with GLK1
Cotyledon de-etiolation is a crucial process during seedling photomorphogenesis that comprises growth pattern reprogramming and the development of photosynthetically active chloroplasts. Studying this process at the molecular level is essential to understand how plants successfully transition to autotrophic metabolism. We studied the role of...

16/07/2025 | Scientific promotion

The sunflower transcription factor HaHB11 increases soybean grain number and heat tolerance across multi-season field trials
Soybean is one of the primary sources of vegetable oil and protein worldwide; however, its yield improvement has lagged behind the other major crops. In this study we explored the potential of sunflower HaHB11, a member of the homeodomain-leucine zipper I subfamily of transcription factors, to enhance soybean yield and heat-stress tolerance. We...

24/06/2025 | Scientific promotion

Mechanical stress induces anatomical changes, tomato early flowering, and increased yield involving ethylene and auxins
Plants have evolved mechanisms to perceive and face mechanical stress (MS) caused by physical forces, including compacted soils, winds, rain, pathogens, and interactions with animals and plants. Previous research indicated that applying mechanical treatment (MT) to Arabidopsis increases both xylem area and seed yield. To explore sustainable tomato...

18/06/2025 | Scientific promotion

Study of two glycosyltransferases related to polysaccharide biosynthesis in Rhodococcus jostii RHA1
The bacterial genus Rhodococcus comprises organisms performing oleaginous behaviors under certain growth conditions and ratios of carbon and nitrogen availability. Rhodococci are outstanding producers of biofuel precursors, where lipid and glycogen metabolisms are closely related. Thus, a better understanding of rhodococcal carbon partitioning...

28/04/2025 | Scientific promotion

The chemoreceptor controlling the Wsp-like transduction pathway in Halomonas titanicae KHS3 binds and responds to purine derivatives
The chemosensory pathway HtChe2 from the marine bacterium Halomonas titanicae KHS3 controls the activity of a diguanylate cyclase. Constitutive activation of this pathway results in colony morphology alterations and an increased ability to form biofilm. Such characteristics resemble the behavior of the Wsp pathway of Pseudomonas. In this work, we...

20/01/2025 | Scientific promotion

Improved serodiagnosis of Trypanosoma vivax infections in cattle reveals high infection rates in the livestock regions of Argentina
Bovine trypanosomosis, caused by Trypanosoma vivax, currently affects cattle and has a significant economic impact in sub-Saharan Africa and South America. The development of new diagnostic antigens is essential to improve and refine existing methods. Our study evaluated the efficacy of two recombinant antigens in detecting specific antibodies in...

13/01/2025 | Scientific promotion

sincFold: end-to-end learning of short- and long-range interactions in RNA secondary structure
Motivation Coding and noncoding RNA molecules participate in many important biological processes. Noncoding RNAs fold into well-defined secondary structures to exert their functions. However, the computational prediction of the secondary structure from a raw RNA sequence is a long-standing unsolved problem, which after decades of almost...

06/01/2025 | Scientific promotion

HYL1's multiverse: A journey through miRNA biogenesis and beyond canonical and non-canonical functions of HYL1
A delicate balance in gene expression, a process highly controlled by post-transcriptional gene silencing mediated by miRNAs, is vital during plant growth and responses to stress. Within the miRNA biogenesis pathway, HYL1 is one of the most important proteins, initially recognized for its role as a cofactor of DCL1. Yet, HYL1's functions...

25/11/2024 | Scientific promotion

An atlas of the tomato epigenome reveals that KRYPTONITE shapes TAD-like boundaries through the control of H3K9ac distribution
In recent years, the exploration of genome three-dimensional (3D) conformation has yielded profound insights into the regulation of gene expression and cellular functions in both animals and plants. While animals exhibit a characteristic genome topology defined by topologically associating domains (TADs), plants display similar features with a...

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ABOUT IAL

  • Who we are
  • Authorities
  • Publications

IAL STAFF

  • Researchers
  • Research Support
  • Fellows

RESEARCH

  • Plant Biotechnology
  • Molecular Biology
  • Molecular Enzymology
  • Small RNAs Biology
  • Molecular Microbiology
  • Evolution of Development

BIOTECH

  • Patents
  • Institutional Projects Unit

LOCATION/CONTACT

Instituto de Agrobiotecnología del Litoral (IAL) - Centro Científico Tecnológico (CCT-Santa Fe)
Colectora Ruta Nac. Nº168 km. 0 - Paraje el Pozo s/n, (CP3000), Santa Fe - Argentina